PRESS RELEASE
PITTSBURGH, Pa. — Cybergenetics, the developer of TrueAllele Know-how, declares the profitable completion of a complete forensic validation that establishes TrueAllele Casework as a scientifically dependable system for decoding advanced DNA mixtures generated by subsequent technology sequencing (NGS).
Working with the Kern Regional Crime Laboratory, Cybergenetics validated the TrueAllele software program for STR information produced by Verogen’s ForenSeq DNA Signature Prep Equipment (Primer Set B) on the MiSeq FGx platform. The outcomes demonstrated that TrueAllele constantly produced correct, delicate, and reproducible interpretations from mixtures containing as much as 5 contributors.
Confirmed Efficiency for NGS Combination Interpretation
As NGS turns into extra frequent in forensic laboratories, the complexity of DNA interpretation has elevated—particularly for mixtures, degraded samples, and contact DNA. This validation confirmed that TrueAllele Casework was already ready to fulfill these calls for.
The research design included:
● Single-source assessments on sensitivity, stochastic results, reproducibility, and 45 recognized reference genotypes
● Combination evaluations involving 21 mock casework samples and a variety of recognized mixtures with various contributor numbers and combination ratios
● Concordance testing evaluating NGS and CE outcomes, equipment variations (Primer Set A vs. B), and plate setup strategies
Throughout all dimensions, TrueAllele Casework proved able to reliably decoding advanced NGS DNA information—paving the best way for forensic labs to increase their capabilities with confidence.
NGS-Validated. Combination-Confirmed. Made within the USA.
With this foundational work accomplished, TrueAllele Casework turns into the primary and solely American-made expertise scientifically validated for decoding advanced DNA mixtures from NGS information. At the moment, as extra labs transfer towards richer DNA testing platforms, TrueAllele stands as a confirmed, trusted resolution for contemporary forensic evaluation.
With validated efficiency on advanced NGS mixtures, DNA forensic crime labs can improve combination interpretation, streamline casework, and enhance downstream court docket outcomes.
Investigators and prosecutors can now carry higher readability to chilly instances, strengthen advanced proof interpretation, and current court-admissible DNA outcomes backed by peer-reviewed science.
Carry the facility of NGS interpretation to your lab with TrueAllele Casework — trusted in your hardest DNA instances. Contact Cybergenetics at this time.
Dedication to Transparency
Topic to entry insurance policies, Cybergenetics gives authorized groups with executable TrueAllele software program for impartial case information evaluation. For scientific transparency, we offer confidential access to laptop supply code.
TrueAllele is a totally automated probabilistic genotyping system that routinely solves advanced or “inconclusive” DNA mixtures—turning what was as soon as thought-about uninterpretable proof into dependable identification outcomes. Since TrueAllele’s introduction in 2001, authorities crime labs have used it to resolve tens of hundreds of felony instances. The pc’s solutions assist each prosecution and protection.
TrueAllele makes the not possible routine — unlocking the facility of DNA proof when justice wants it most.
Contact Cybergenetics at this time to carry the facility of American-made forensic expertise to your company.
